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Histatin-8 [Hemagglutination - Inhibiting Peptide (HIP)]

Name
Histatin-8 [Hemagglutination - Inhibiting Peptide (HIP)]
Molecular structural formula
Purity
≥95%
CAS Number
127637-03-0
Formula
C70H99N25O17
MW
1562.73
Target
Fungal
Sequence
Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr
Sequence Shortening
KFHEKHHSHRGY
InChIKey
MSVLPSBDYOVCST-ZUDWGGBQSA-N
References
[1]. Neshani A, et al. Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections. Microb Pathog. 2020 Sep;146:104238. [2]. Matheson S M G, et al. Investigating the Effects of Hydrophobicity and Charge on the Therapeutic Ability of the Antimicrobial Histatin 8 Peptide for Potential Use in Oral Applications. International Journal of Biology, 2013.
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Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent anti-fungal peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research.